Thursday, June 18th 2015   08:40-09:00 Registration 09:00 OPENING OF THE CONFERENCE Dr. Marco Kirm, Vice-Rector for Research, University of Tartu, Estonia Dr. Tõnu Esko, Estonian Genome Center, University of Tartu, Estonia 09:15-10:40 OPENING SESSION Chair: Prof. Andres Metspalu, University of Tartu, Estonia Prof. Uta Francke, Stanford University, 23andMe, US "DNA is not a diagnosis: Interpreting and Communicating Sequence Variants" Dr. Heiko Runz, Merck Research, US "Leveraging human genetics for drug discovery" 10:40-11:00 COFFEE / TEA 11:00-12:45 SESSION I Chair: Dr. Mait Metspalu, Estonian Biocentre, Estonia Dr. Garrett Hellenthal, UCL Genetics Institute (UGI), Department of Genetics, Evolution and Environment, UK "The genetic history of the United Kingdom: the POBI project" Dr. Luca Pagani, Sanger Center, UK "450 diverse high coverage whole genome sequences reveal ancient population admixture in modern human populations" Prof. Boris Lenhard, Faculty of Medicine, Institute of Clinical Science, Imperial College of London, UK "Promoters and long-range regulation in vertebrate development" 12:45-13:55 LUNCH 13:55-15:40 SESSION II Chair: Dr. Lili Milani, University of Tartu, Estonia Prof. Claes Wadelius, University of Uppsala, Sweden "The secrets of GWAS are written in the reads" Dr. Mia Wadelius, Department of Medical Sciences, University of Uppsala, Sweden "Pharmacogenomics in the clinic - warfarin and other examples" Dr. Valtteri Wirta, Science for Life Laboratory, Sweden "Implementing exome and whole-genome sequencing for clinical diagnosis of inherited disorders" 15:40-16:00 COFFEE / TEA 16:00-17:45 SESSION III Chair: Prof. Ursel Soomets, University of Tartu, Estonia Prof. Mart Saarma, Institute of Biotechnology, University of Helsinki, Finland "Neurotrophic factors for neurodegenerative diseases" Prof. Julian Knight, Wellcome Trust Centre for Human Genetics, Oxford, UK "Understanding context specific eQTL informative for immune-related disease" Dr. Andreas Pfenning, Massachusetts Institute of Technology, Computer Science and Artificial Intelligence Laboratory, US "Interpreting GWAS loci through epigenomics: insights into Alzheimer’s and obesity" 20:00 BUFFET DINNER served at restaurant Atlantis Friday, June 19th 2015   09:30-11:00 SESSION IV Chair: Prof. Andres Metspalu, University of Tartu, Estonia Prof. Reiner Leidl, Munich School of Management, Ludwig-Maximilians University, Germany "Health economics can help to improve use of genetic information in health care" Prof. Jacques Beckmann, Swiss Institute of Bioinformatics, Switzerland "Personalised approaches to disease and health" Luc Smink, District Manager for Northern Europe, Illumina Inc, "Human Genome Analysis at Scale" 11:00-11:20 COFFEE / TEA 11:20-13:05 SESSION V Big Data Driven Medicine Chair: Prof. Jaak Vilo, University of Tartu, Estonia Dr. Ali Torkamani, Director of Genome Informatics, Scripps Translational Science Institute, US "The Scripps Idiopathic Diseases in Man Initiative" Prof. Peeter Ross, Tallinn Technical University, Estonia "Integration of genome, health and medical data in personalised medicine" Prof. Charles Auffray, European Institute for Systems Biology and Medicine Université de Lyon, France "Revolutionizing healthcare and wellness management through systems medicine" 13:05-14:15 LUNCH 14:15-16:00 SESSION VI Neurobiology Chair: Dr. Tõnu Esko, University of Tartu, Estonia Prof. Patrick Sullivan, UNC School of Medicine, US/ Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Sweden "Schizophrenia genomics: where we are & where we need to be" Prof. Cynthia Bulik, UNC School of Medicine, US/Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Sweden "Viewing Eating Disorders Through New Lenses: Genes & Bugs" Dr. Reedik Mägi, Estonian Genome Center, University of Tartu, Estonia "Genetics of obesity and beyond" 16:00 CLOSING OF THE CONFERENCE