Friday, 08. June 2012   09:00 OPENING OF THE CONFERENCE Prof. Alar Karis, Rector of the University of Tartu, Estonia 09:05-10:25 OPENING SESSION Chair: Prof. Andres Metspalu, Estonian Genome Center, University of Tartu. Prof. Andrea Ballabio, Director, Telethon Institute of Genetics and Medicine (TIGEM), Italy The Transcriptional Control of Cellular Clearance ad Energy Metabolism Prof. Aldons J. Lusis, The Lusis Laboratory, University of California, LA, Genetic architecture of diet-induced obesity in the mouse 10:25-10:45 Coffee/tea break 10:45-12:35 SESSION I Chair: Prof. Pärt Peterson, Institute of General and Molecular Pathology, University of Tartu. Prof. Oluf B. Pedersen, Steno Diabetes Center, Denmark Exome-sequencing-driven association studies of common metabolic traits Prof. Johan Björkegren, University of Tartu / Karolinska Institutet, Sweden The missing heritability of complex traits – hidden in the environmental contexts of GWA datasets Dr. Matthias Nees, VVT Technical Research Centre, Finland From Images to Genes to Functions 12:35-13:45 Lunch 13:45-15:45 SESSION II Chair: Dr. Krista Fischer, Estonian Genome Center, University of Tartu. Dr. Nuala A. Sheehan, University of Leicester, UK Participant Identification in Genetic Association Studies: Methods and Practical Implications Prof. Yudi Pawitan, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Sweden Statistical challenges in the analysis of high-throughput molecular data Prof. David Balding, UCL Genetics Institute, UK Kinship, heritability and genetic effect sizes 15:45-16:05 Coffee/tea break 16:05-18:00 SESSION III Chair: Dr. Mait Metspalu, Estonian Biocenter. Prof. André Uitterlinden, Erasmus Medical Centre, Rotterdam, The Netherlands Genome(wide) Explorations in Human Cohort Studies Prof. Claudio Franceschi, Department of Experimental Pathology, Laboratory of Immunology, University of Bologna, Aging and Longevity: Models + Omics --> Genetic Basis Prof. Eske Willerslev, Centre for GeoGenetics, University of Copenhagen, Denmark Ancient Human Genomics 20:00 Buffet Dinner served at restaurant Atlantis Saturday, 09. June 2012   09:00-11:00 SESSION IV Chair: Prof. Sulev Kõks, Institute of Physiology, University of Tartu. Dr. Iiris Hovatta, University of Helsinki, Finland A cross-species neurogenomics approach to anxiety Prof. Martien Kas, Department of Neuroscience and Pharmacology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, The Netherlands Cross-species genetics of behavioral traits; relevance for psychiatric disorders Prof. Tiina Paunio, Institute of Clinical Medicine, University of Helsinki, Finland Genetic background for depression and sleep disturbance 11:00-11:20 Coffee/tea break 11:20-13:20 SESSION V Chair: Riin Tamm, Estonian Genome Center, University of Tartu. Prof. Albert de la Chapelle, Comprehensive Cancer Center, The Ohio State University, US The genetic predisposition to papillary thyroid cancer Prof. Adrián LLerena, Director, Clinical Research Centre Extremadura University Hospital, Badajoz, Spain CYP2D6, depression, antidepressant drugs and Suicide Dr. Tambet Teesalu, Cancer Center, Sanford-Burnham Medical Research Institute, La Jolla, USA; University of Tartu, Institute of General and Molecular Pathology, Estonia Cancer drug delivery using tumor penetrating peptides 13:20-14:30 Lunch 14:30-15:50 SESSION VI Chair: Tõnu Esko, Estonian Genome Center, University of Tartu. Prof. Alexandre Reymond, University of Lausanne, Center of Integrative Genomics, Switzerland Genome structure and gene expression Dr. Lude Franke, University of Groningen, The Netherlands Identification of the downstream consequences of genetic variants through genetical genomics and gene network reconstruction 16:00 CLOSING OF THE CONFERENCE